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It is currently unclear how these processes are precisely modulated, as the degradation or inhibition of related proteins does not occur synchronously even when copper ion concentrations are similar

Akin to several well-established post-translational modification (PTM) processes, e.g., phosphorylation, acetylation, and methylation, S -glutathionylation has recently been determined to play an important role in regulating protein function

Specifically, while chronic, low-dose SFN may be ideal for prevention, its use as an adjunct to chemotherapy in established cancers requires careful scheduling to avoid potential protection of tumor cells

Pathways are specific

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