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Preclinical studies suggest that statins can reduce BBB permeability by enhancing the expression of tight junction proteins and decreasing the activity of MMPs, which are implicated in the degradation of tight junctions (Liu et al., 2021)

Determination of total phenolic content of ethanol extract of broken bone twigs ( Euphorbia tirucalli Linn.) by Folin-Ciocalteu method spectrophotometrically

3.2.3 Treatment of pulmonary diseases Idiopathic pulmonary fibrosis is a chronic and progressive interstitial lung disease characterized by excessive fibrosis of the lung tissue and is associated with high morbidity and mortality rates ( ERCs also exhibit multipotent therapeutic potential in Idiopathic pulmonary fibrosis treatment (Zhao et al., 2018a)

[96] show that erinacine A inhibited pro-inflammatory cytokine expression in BV-2 microglial cells, suggesting neuroprotective potential, and Yang et al