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Emerging evidence suggests that autophagy may significantly contribute to the pathogenesis of PCOS ( Beyond follicular dynamics, autophagy is essential for maintaining normal oocyte and granulosa cell function, as well as modulating insulin signaling ( e.g ., IL-1, IL-18), thereby mitigating chronic inflammation

Activation of Nrf2 by NFT To gain insight into pathways that may be involved in the observed increase in glutathione levels, we conducted high throughput targeted RNA sequencing of samples from HepG2 cells

Biochemical and biophysical research communications , 280 (1), 132138

261 Pyruvate kinase M2 (PKM2), another key glycolytic enzyme, is stabilized by the deubiquitinase USP20, making USP20 a potential therapeutic target

Emphasize the importance of not sharing insulin syringes with others to prevent cross-contamination and the spread of infections