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long-term safety and efficacy in humans have not been fully established

Moreover, some recent case-control studies have documented cerebral pantothenic acid deficiency in patients with Alzheimers disease (20) and in those with Huntingtons disease (21)

This activation induced the expression of pro-fibrotic genes such as -smooth muscle actin and fibronectin, leading to TM fibrosis and obstructed aqueous humor outflow (Wan et al., 2021