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Like any injection, there is some discomfort during the injection but it is minimal

Once absorbed, it converts enzymatically, first to retinaldehyde, then to retinoic acid, which binds nuclear retinoic acid receptors (RARs) and drives cell-level changes

Future work will include a more detailed model of the blood compartment and inter-organ regulation of glutathione and its component amino acids

Research has identified effects on genes controlling antioxidant responses, inflammatory processes, and cellular repair mechanisms

Conclusion and perspectives In this review, we briefly summarized the pathophysiology of IBD and current clinical management strategies