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Therefore, although FH-deficient cells experience a chronic oxidative stress, GSH levels are not compromised in these cells

NAC decreased both cellular ROS production and autophagy, implicating redox thiol signaling as an important regulator of autophagy

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The most commonly used form of KD includes long-chain fatty acids and was initially introduced by Wilder in 1921 for the treatment of drug-resistant epilepsy in children [27]

Several NADs, including ASOs, aptamers, siRNAs, and mRNA vaccines, have been adopted as vaccines for treating rare genetic diseases, cancer, ophthalmic diseases, CVDs, and infections