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For example, in an energy-restricted IF intervention using a modified fasting regimen of 5:2 (5 days normal feeding:2 days fasting), 12 weeks of energy restriction elicited approximately a 5% reduction in weight (62)

Inhibition of vascular smooth muscle cell (VSMC) proliferation The proliferation and migration of normally quiescent VSMCs are central features of vascular diseases, including atherosclerosis and coronary restenosis (when treated arteries become blocked again) (47)

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