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Under diabetic conditions, disruption of the regulation of microglia activity by hyperglycaemia occurs through a number of mechanisms, including overproduction of reactive oxygen species (ROS) and glycosylation end products (AGEs), and reduced elimination of A

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KimBKimHSJungEJLeeJYTsangBLimJMet alCurcumin induces ER stress-mediated apoptosis through selective generation of reactive oxygen species in cervical cancer cells

Global non-metric multidimensional scaling analysis of experimental variables To evaluate the overall impact of Clc in gluten-fed DQ8-D d -villin-IL-15tg mice, we conducted a global NMDS analysis incorporating a comprehensive set of experimental variables, including gut and plasma auto-Ab levels, plasma cytokines and immunoglobulins, haematological profiles, gliadin concentrations in the stomach and small intestine, body-weight changes, food and water intake, body-mass index and Lee index, faecal humidity and pH, organ weights, morphometric and histological parameters, MLN lymphocyte populations and caecal microbiota composition (Fig

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