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Additionally, we sought information regarding standards of care or clinical guidelines that recommend that a dental infection be addressed ( before proceeding with the immunosuppressive treatment or the administration of drugs or whether oral antibiotics would be prescribed to resolve the infection and that the therapy would advance without direct dental or oral services to address the infection

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This bidirectional modulation gives the compound a homeostatic quality: it pushes tissue toward repair rather than simply amplifying any single pathway

It influences the dopamine and serotonin pathways