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Mesna The antioxidant agent mesna (Mesnex) was developed to mitigate the urinary tract toxicity of some chemotherapy drugs, such as cyclophosphamide and ifosfamide, without reducing their antitumor effects (Brock 1980)

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5-Amino-1MQ is a small-molecule quinolinium compound not a peptide that selectively inhibits nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme involved in the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor

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Here in this study, the authors revealed that this plant extract increased the concentration of GABA by 240% in groups treated with 4 and 8 mg/kg, which is almost 3-fold higher than the increase in the sodium valproate group (96%)