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Melasma: a clinical, light microscopic, ultrastructural, and immunofluorescence study

muciniphila ), which helps explain their impact on systemic inflammatory markers and cardiometabolic risk (157)

In vitro permeation studies show cumulative skin transport reaching 40.1 4.7 g/cm for coated liposomal VC vs 19.2 3.2 g/cm for conventional liposomes and ~9 g/cm for solution, demonstrating markedly higher deposition in deeper layers