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Molecular cell 86(2):407-422.e6, 2026

The interesting point about the binding of drugs to aptamers is that by changing the length of the aptamer and its physicochemical features, the number of conjugating molecules can be increased without any particular effect on the affinity and specificity of the aptamer [211, 216]

Because of this unfounded fear of overdosing on B12, doctors often drastically reduce treatment, or stop it altogether

By working closely with your healthcare team and following a personalized kidney-friendly diet, you can support your kidney health and overall well-being while living with CKD