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Changes may restrict themselves to a cluster called the CREST Syndrome, named after the characteristic symptoms of calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly (fingers and toes), and telangiectasia (dilation of capillaries and minute arteries, forming a variety of tumors), all names given to various ones of the above described symptoms

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It helps in the treatment of peripheral neuropathy, anemia, fatigue, and neurodegenerative conditions , ensuring optimal nervous system function

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