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Regulatory T cells: history and perspective

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The oxidative stress induced by Hcy due to 1) gut microbiome lacking diversity, 2) compromised methylation (genetic or epigenetic), 3) chronic inflammation elicited by residual spike protein S in LC, or 4) persistent SARS-CoV-2 induced T cell lymphopenia reactivating dormant viruses all conspire to overwhelm mitochondria lacking an antioxidant shield

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HMGB1 which is the biomarker that was evaluated as a therapeutic target of DCM and NF-kB, a nuclear transcription factor, both of which cause inflammation, contribute to myocardial damage