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These released exosomes can then modulate immune response in other cells through a payload of inflammatory cytokines, like TNF-alpha, or through microRNA s that decrease inflammation.[ref] Mast cell release of exosomes has been shown to increase the formation of collagen in fibroblasts, which can lead to fibrosis (including pulmonary fibrosis, IPF)

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2010 Dec;27(4):384-90

Denmark Studies suggest that by removing the senescent cells reduces inflammation, clears damaged tissue, and creates space for healthy cells to thrive

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