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Description

Genetic or pharmacological SIRT5 inhibition impairs in vitro transformation of mouse hematopoietic cells by several myeloid oncogenes, including MLL-AF9, and attenuates in vivo leukemogenesis

Kuster, I

[Updated 2022 Oct 10]

3A, B, the average relative numbers of NeuN-negative cells [quantified by ImageJ 66 ] (29.5%) increased by 27.9% in the ROT group as compared to those of the NC group (1.6%) ( P = 2.7 10 3 )