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Finally, we describe the limited existing evidence for the use of isatuximab or daratumumab after disease progression on prior anti-CD38 mono- or combination therapy, highlighting the need for additional clinical evaluations to define optimal anti-CD38 antibody therapy selection and sequencing in RRMM

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This is because even when a psoriatic plaque is resolved, IL-17 and IL-22-producing cells remain in the epidermis and can be triggered into recruiting circulating T cells, producing a plaque relapse

It is essential for the production of the myelin sheaththe protective coating that surrounds nerve fibers