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Calcium plays a very important role in the body

Enhances skin brightness and reduces dark spots with Vitamin C and Glutathione, while improving elasticity for a glossy, moisturized appearance

FIGURE 1 4 Role of natural products 4.1 Herbal products 4.1.1 Baicalein Baicalein is a chemical compound derived from the dried root of the Scutellaria baicalensis plant (Labiatae) (Li et al., 2012)

3 Key mechanistic pathways and synergistic actions In clinical application, TCM is often administered in multi-herbal formulations (7880), which typically involve multiple herbs targeting the same signaling pathway (78, 81) or a single herb acting through multiple mechanisms for the same disease (82, 83)

This review focuses on the main substrates, inhibitors and reactions played by cytosolic GSTs, with an eye on their relevance for human disease