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142,222,225,385,386,387 It has also been demonstrated that the enzymes in glycolysis (e.g., GLUT4, HK1, GSK3B, and GAPDH), the enzymes (e.g., PDPR PDHA1, and PDHX) in carbohydrate metabolism, and most enzymes in ETC and ATP synthesis are assigned as ADP-ribose amino acid acceptor

IGF-1 in cartilage metabolism IGF-1 promotes cartilage anabolism Proteoglycan is an essential component of the ECM

Vitamin B12 deficiency can affect people of all ages, but certain groups are more vulnerable due to dietary habits, health conditions, or lifestyle factors

The exact reasons and mechanisms regarding the failure of these studies to produce the expected beneficial effects remain largely unknown

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