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During the 7-day treatment schedule, MP-13 maintained stable antinociception without tolerance development, as evidenced by the unchanged microglial cell count in the periaqueductal gray, indicating that chronic exposure did not trigger neuroinflammatory adaptationa process in which microglia become activated, release pro-inflammatory cytokines, and contribute to opioid tolerance

More than skin deep: Using polymers to facilitate topical delivery of nitric oxide

Whether clumsily knocking into the corner of a table or losing sleep over a stressful situation, life causes our cells to get inflamed

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