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Inhibition of lactic, alcohol and glucose-6-phosphate dehydrogenases by cigarette smoke and components thereof

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While some interventions, such as the use of caspase inhibitors that directly prevent apoptotic cell death [556, 557], are readily classified as neuroprotective, others, including anti-inflammatory agents or metabolic modulators, have more systemic or indirect effects, rendering their categorization less straightforward

The discrepancies observed across studies likely stem from variations in patient selection criteria, L-carnitine dosing regimens, and importantly, the sensitivity and methodology of apnea monitoring

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