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Severe acute respiratory syndrome coronavirus infection of mice transgenic for the human Angiotensin-converting enzyme 2 virus receptor

J Transl Med (2012) 10:88

La dopamina es un neurotransmisor cuya sntesis y liberacin dependen crticamente de la disponibilidad de ATP en las terminales presinpticas, dada la actividad de la tirosina hidroxilasa (enzima limitante de la sntesis dopaminrgica) y de los transportadores vesiculares VMAT2 que requieren gradiente de protones

This may be attributed to the role of metformin in reducing the production of sFlt-1 and soluble endoglin by endothelial cells, trophoblasts, and syncytiotrophoblasts, and modulating anti-angiogenic factors at the mitochondrial level (Romero et al., 2017)