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9 Proof-of-concept treatments were tested on patient fibroblasts and Pfa1 cells, which were knocked out of endogenous GPX4 and transfected to overexpress human mScarlet-tagged GPX4 WT (red) or GPX4 R152H (blue)

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Yang M, Vousden KH (2016) Serine and one-carbon metabolism in cancer

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