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Assays and studies on the tongues of irradiated rats showed that mitochondrial ROS production plays a role in mucositis and is influenced by the NF-kappa-B and NLRP3 activation (both are known to activate inflammatory pathways that increase the expression of genes responsible for causing mucositis) [49]

Avocados also contain glutathione, a chemical that functions as an antioxidant

Liver disease predisposes patients to gastrointestinal ulceration because of impaired mucosal blood flow, which is a result of dehydration and portal hypertension and decreased clearance of histamine and gastrin.6 Evidence of gastrointestinal bleeding may include melena, hematochezia, or an increased serum BUN to creatinine ratio

HR is deficient in many tumours, leading to increased sensitivity to DNA-damaging agents that are used widely in clinical settings

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