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Approximately, 90% of ALS cases are sporadic (sALS), while 10% are familial (fALS)

10.1126/science.adl3787 28 CorboJ.-H.ChungJ

Thus, disruption of the gene encoding either of these -type TrxRs is compensated by a partial re-distribution of product from the other gene into the deficient sub-cellular compartment (Meyer et al., 2008

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