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The proposed mechanism centers on modulation of the nitric oxide system: BPC-157 counteracts L-NAME-induced eNOS blockade in rat models and supports vascular sprouting through VEGFR2 internalization (Hsieh et al., J Mol Med , 2017)

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Oleuropein inhibits A1-42 peptide oligomerization in AD and tau fibrillization in AD and other tauopathies [176,177]

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Increased expression levels of genes associated with autophagy, oxidative stress and inflammation were observed in copper-treated HepG2 ATP7B-KO cells and in primary hepatocytes from patients with WD