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The micro-needle component facilitates controlled disruption of the stratum corneum to enhance topical peptide absorption in dermatological research models

Hydroxocobalamin binds more tightly to serum proteins, creating a depot effect that allows for slower release and prolonged availability to tissues

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After systematically dissecting the molecule into fragments, they found that the C-terminus (amino acids 177 to 191) preserves the lipolytic effect without the other GH functions