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Specifically, there was attenuated inflammatory response to a chemical skin irritant, decreased TEWL, and reduced skin roughness and scaling

[78] N-acetylcysteine may also destabilize the disulfide bonds in clotting factors and modestly prolong the International Normalized Ratio, though this may not be clinically significant

However, its efficacy varies between patients and with different classes of chemotherapy, and a large proportion of patients may still lose up to 50% of their hair

Nat Methods 8 , 424429 (2011)