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GHK-Cu is most stable and effective at a neutral pH, around 6 to 7

Because it has a stimulating, focus-oriented effect, a small number of people notice increased anxiety

Furthermore, glycosylation increases DATs susceptibility to bind to various drugs such as cocaine (Li et al., 2004) and reduced glycosylation of DAT in the human striatum and midbrain leads to increased PD susceptibility ( 4.5 Nitrosylation and oxidation Nitric oxide-mediated DAT nitrosylation was found to contribute to DAT regulation

This is based on currently available evidence and individual circumstances may differ