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Inhibition of USP1 activates ER stress through Ubi-protein aggregation to induce autophagy and apoptosis in HCC

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Li F-R, Yu Y, Du Y-M, Kong L, Liu Y, Wang J-H, Chen M-H, Liu M, Zhang Z-X, Li X-T, Ju R-J

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(A) After 24 h of incubation, HCT-116 cells were stained with Hoechst 33342, after which cell nuclei were observed under a microscope for detection of apoptosis

Similar content being viewed by others Background Taxanes are considered first-line chemotherapeutic agents often used in several cancers including those of the breast, ovaries, prostate, gastric, head and neck, and non-small lung cancers [1]