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Isatuximab binds to the CD38 epitope via its gamma heavy chains, inducing cell death through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) and apoptosis 146,147

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A 2023 paper in Pharmaceuticals (PMID: 37242459) documented anxiolytic, anticonvulsive, and antidepressant-like effects in animal behavioral assays and reported that BPC-157 attenuated benzodiazepine tolerance development and counteracted serotonin syndrome in rats