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In addition, a meta-analysis of four clinical trials demonstrated that after three to 6 months of metformin use it significantly reduced vitamin B 12 levels [85]

Depression and anxiety are psychiatric disorders that occur in conjunction with chronic pain and contribute to the intensity of symptoms experienced by individuals with chronic pain, interfere with effective coping skills necessary to manage chronic pain, and affect treatment outcomes (20)

The injection bypasses digestion, allowing for faster absorption compared to oral supplements

Untreated vitamin B12 deficiencies can lead to neurological issues or pernicious anemia which can occur when your body does not have enough vitamin B12 to produce the amount of red blood cells it needs

Dosage: Infants and Children (up to 19 years): 0.5 mL