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The first model predicts that ER homeostasis will be preserved by ET, whereas the second predicts that it will be compromised, because impairment of the UPR is known to aggravate ER stress (Walter and Ron, 2011)

After injection, the needle was left in place for additional 10 min to avoid drug reflux

These data suggest that the Q41A may assist ENL in making more favorable contacts with CRBN in the presence of ( S )-dHTC1

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[DOI] [PMC free article] [PubMed] [Google Scholar] Renga B, Cipriani S, Carino A, Simonetti M, Zampella A, Fiorucci S (2015)