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According to research published in the NIH database, approximately 16-20% of severe asthma patients have elevated eosinophils, making them ideal candidates for IL-5 inhibitors for asthma . Type 2 inflammation asthma drives this eosinophilic phenotype, where IL-5 protein triggers excessive eosinophil production that attacks airway tissue

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Research in 2026 suggests that elevated NNMT activity, common in aging and metabolic dysfunction, can deplete NAD+

In conclusion, while OHE may suffice for simpler and more independent classification tasks, embedding-based models like ClinicalBERT clearly outperform traditional methods in complex and multifactorial prediction tasks