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NAD+ / SIRT1: Associated with elevated NAD+ and SIRT1 activation in preclinical studies [2] [3]

Reactive oxygen species (ROS), or free radicals, are byproducts of normal metabolism, produced constantly within the body

In a 2019 meta-analysis, people with constipation who exercised aerobically had improved constipation symptoms, along with better quality of life and well-being 11