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Glutathione, as a master antioxidant, is critical for neutralizing harmful reactive species, protecting cells, and maintaining heart health

This action protects alveolar epithelial cells against inflammation, injury, and apoptosis via the repression of prolyl hydroxylase 2/HIF-1/MAPK signaling, suggesting its potential in treating COPD and pulmonary fibrosis (Guan et al., 2020)

Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

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Conclusions and Future Perspectives The pathogenesis of brain aging can be attributed to three interrelated pathological processes: the progressive accumulation of intracellular oxidative stress, dysregulation of energy metabolic networks, and the persistent deterioration of mitochondrial function