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The CPT1 subunit in the heart, skeletal muscle, and liver is inhibited by malonyl CoA [23], with heart and skeletal muscle being more sensitive to the regulation of this enzyme, and the brain-specific CPT1 subunit having a high affinity for malonyl CoA [24]

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Also, high levels were associated with worse outcomes in people with primary sclerosing cholangitis, an immune-related disease of the liver [34]

Intake of sufficient nutrients, too, is important

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