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Description

Nicotinamide N-methyltransferase (NNMT) is an enzyme that methylates nicotinamide using SAM as a methyl donor

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They are typically administered intramuscularly (into the muscle)

Originally developed by Metabolic Pharmaceuticals Ltd

Following single dose of subcutaneous administration of 1.28 mg of EGRIFTA WR (11.6 mg/vial formulation) in healthy subjects, the mean [coefficient of variation (CV)] AUC0-inf was 1172 (48%) pg.h/mL