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The individual effects of sex hormones tend to counterbalance each other via the expression and function of cardiac ion channels that regulate action potentials to coordinate a normal heartbeat

including 1) excessive daytime sleepiness (EDS), 2) sleep-related breathing disorders (SBDs), such as obstructive sleep apnoea syndrome (OSAS), 3) central hypersomnia and secondary narcolepsy, and 4) circadian rhythm sleepwake disorders (CRSWDs) [125], classified according to the third edition of the International Classification of Sleep Disorders (ICSD-3) of the American Academy of Sleep Medicine [126]

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Taquet, M., Dercon, Q