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The most common of them is p.C282Y, when cysteine replaces tyrosine in position 282 of the HFE gene

Medication use during pregnancy, with particular focus on prescription drugs: 1976-2008

Due to these great properties, tetrasulfide bonds have been utilized in the development of redox-responsive DDSs

Among these, the abnormal aggregation of -synuclein (-syn) to form Lewy bodies, mitochondrial dysfunction, oxidative stress, impaired protein homeostasis, and neuroinflammation (the activation of microglia and astrocytes leads to the release of various inflammatory factors, such as tumor necrosis factor- (TNF-) and interleukin-1 (IL-1), which exacerbate neuronal damage) constitute the key links in the pathophysiology of PD [6, 7]

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