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Serious adverse events (SAEs) were defined as: 1) critical or life-threatening complications

The data also indicate that pyridoxine supplementation only reduces the hyperhomocysteinemia detected after oral methionine administration in vitamin B 6 -deficient patients or in heterozygotes for CBS deficiency

The company submitted a New Drug Application to the United States Food and Drug Administration in December 2025, based on the REDEFINE 1 and REDEFINE 2 results, with a decision anticipated late in 2026

The 10-year T-note now yields 4.56% - well off its peak but up 94 basis points from its recent low of 3.62% in September 2024

For a standard 10mg vial reconstituted with 2ml of bacteriostatic water (BAC water), the concentration is: 10mg / 2ml = 5mg/ml This means every 1ml of solution contains 5mg of peptide