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Ann Chir 51(2):136139 de Arajo GR, Rabelo ACS, Meira JS, Rossoni-Jnior JV, de Castro-Borges W, Guerra-S R, Batista MA, Silveira-Lemos D, Souza GHB, Brando GC, Chaves MM, Costa DC (2016) Baccharis trimera inhibits reactive oxygen species production through PKC and down-regulation p47phox phosphorylation of NADPH oxidase in SK Hep-1 cells

6 Core characteristics, distribution, and phenotypic plasticity of microglia 6.1 Microglial heterogeneity, activation signaling, and biphasic regulation in neurodegeneration Microglia, which constitute 1015% of brain cells, play a critical role in the innate immune response and neuroplasticity (Figure 3)