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At present, no Good Manufacturing Practice (GMP)-compliant production pipeline has been formally established for PDEVs

This review presents a synthesized perspective on the pathophysiological mechanisms and therapeutic strategies for gout and hyperuricemia, with a nuanced focus on delineating the evolving role of DDS

Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene

A.Da Silva, J.Dort, Z.Orfi, X.Pan, S.Huang, I.Kho, E.Heckel, G.Muscarnera, P.Piet van Vliet, L.Sturiale, A.Messina, D.Romeo, C.D.M.van Karnebeek, X.Wen, A.Hinek, T.Molina, G.Andelfinger, B.Ellezam, Y.Yamanaka, H.J.Olivos, C.R.Morales, J.Joyal, D.J.Lefeber, D.Garozzo, N.A.Dumont, A.V.Pshezhetsky N -acetylneuraminate pyruvate lyase controls sialylation of muscle glycoproteins essential for muscle regeneration and function Science Advances 9(26), (2023) DOI: Abstract: Deleterious variants in N -acetylneuraminate pyruvate lyase (NPL) cause skeletal myopathy and cardiac edema in humans and zebrafish, but its physiological role remains unknown

(2025) revealed that lactate dynamically regulates histone lactylation at H4K5la, H4K8la, and H4K12la during meiotic prophase I in mouse spermatogenesis