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[DOI] [Google Scholar] 147.Miranda O.R., Chen H.T., You C.C., Mortenson D.E., Yang X.C., Bunz U.H.F., Rotello V.M

Nuclear sterol regulatory element-binding proteins activate genes responsible for the entire program of unsaturated fatty acid biosynthesis in transgenic mouse liver

However, there are no large-scale, long-term human safety trials

Previous metazoan projects have been restricted to Deuterostomia (for example, Homo , Mus and Ciona ) and the ecdysozoan clade of the Protostomia (for example, Drosophila , Caenorhabditis and Brugia )