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IGF-1 also enhances the activity of T-lymphocytes, which are essential for cell-mediated immunity and the destruction of infected or cancerous cells (Alpdogan et al., 2003)

A common example is sulforaphane, found in cruciferous vegetables, which activates Nrf2, a master regulator of antioxidant pathways.74 Similarly, coenzyme Q10 supports mitochondrial health and reduces oxidative stress-related senescence.75 Key Senolytic Compounds and Their Mechanisms of Action A variety of compounds have been identified as potential senolytics, each with distinct mechanisms of action