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Neuron 37 : 649661 Howard AD et al

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It binds to ghrelin receptors, triggering short pulses of growth hormone release without significantly impacting cortisol or prolactin levels

In practical terms that means deeper sleep, better recovery, improved body composition, and over months, meaningful shifts in lean muscle, fat distribution, skin quality, and overall steady-state energy

Sermorelin supports natural growth hormone (GH) production and may provide broader metabolic and muscle growth benefits with fewer concerns about dependency