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Spatial metabolomics, in particular, integrates imaging mass spectrometry with molecular profiling to visualize metabolite distributions within intact tumor tissues, enabling the mapping of metabolic gradients associated with oxygen deprivation and therapy resistance

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J Hum Genet 53(11):10121015 Trinh J, Zeldenrust FM, Huang J, Kasten M, Schaake S, Petkovic S, Madoev H, Grnewald A, Almuammar S, Knig IR (2018) Genotype-phenotype relations for the Parkinsons disease genes SNCA, LRRK2, VPS35: MDSGene systematic review

It exerts key roles in all aspects of metazoan physiology, from conferring physical and mechanical properties on tissues and organs to modulating cellular processes such as proliferation, differentiation and migration