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Description

Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis

Both the kidneys and liver appeared normal upon gross examination, and histopathological analysis confirmed no abnormalities in these organs (717)

However, to our knowledge, these aspects have not been systematically studied

The practical implication is uncomfortable but honest: a 12 week window is a handling convention, not a measured stability specification for any particular vial, and degradation is not something that can be seen in a clear solution