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Using chemical inhibitor and KO mice, c-Jun amino-terminal kinase 2 (JNK2) was demonstrated to play a major role in morphine- but not fentanyl-induced G protein uncoupling (Melief et al., 2010)

Genomic approaches to the deconvolution of microenvironmental cellular subtypes are increasingly utilised in oncology research

Ketones and lactate increase cancer cell stemness, driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomics

Discussion In this study, we performed FACS-based genome-scale CRISPR screens to identify critical modulators of hepatic surface LDLR abundance

Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins