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Loss of Lgr5 + stem cells in response to severe (often transmural) injury requires additional regenerative capacities in the intestine, involving quiescent slow-cycling cells located at the +4 position in the crypt, de-differentiated epithelial cells and reserve stem cells 35

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A method for enhancing immunological resistance to mycobacteria, such as Mycobacterium Tuberculosis, in mammalian patients, comprising: administering reduced glutathione in a liposomal formulation to said patient displaying symptoms of tuberculosis

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